Triaxiansilk.com

http://www.xkcd.com/540/

So, I imagine more than one of you are also aware of teh awesome meme'ness known as XKCD. Note, the Star Trek Fanfiction reference in this particular comic.

If you've never read XKCD, I warn you, you can easily blow 2 hours just going into the archives.

I remember that one . I catch up once in a while. A very funny post apocalyptic comic is Gone With The Blastwave http://www.blastwavecomic.com/.
Another good one is Ctrl+Alt+Del http://www.ctrlaltdel-online.com/

CAD is simply awesome. I'm going to throw Jeph Jacques' Questionable Content to the mix.